Anti-ribosomal Ab (ARIA) is an autoantibody which may be seen in IFA tests for APCA...causing positive staining in the non-parietal gastric glandular cells. We use the FLUORO-KIT test system with cryostat sections of rat kidney and stomach, and or rat liver as the substrate at a beginning dilution of patient's serum of 1:20. The use of animal tissue avoids interference from HLA and/or blood group Abs that may occur were human substrate used. Incidental Abs may show up in this system such as ASMA, APCA, ANA, ARA, ABBA, anti-canalicular Ab, and anti-liver cell membrane Ab.

Associations with undetectable Ab:

• normalcy

Associations with elevated levels:

• SLE with renal involvement