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IHC TABLE for Renal Tumors
Tumor Type ck7 LMW
C
K
8
&
1
8

E-
cad
her
in

 C
K
1
3		 C
K
1
9		 V
I
M
E
N
T
I
N		 U
E
A
1		 C
D
3
4		 D
E
S
M
I
N		 A
C
T
I
N		 H
M
B
4
5		 N
S
E
&
S
1
0
0		 C
H
R
O
M
O
G
R
A
N
I
N		 N
C
A
M		 LCA
Clear cell RCC
wk+ unless low grade & then strong+
 + few+ - +/- + - - - - - - - - -
Chromophil RCC   +   - +/- + - - - - - - - - -
Renal oncocytoma [EGFR -3]

-
(50%+2)
+
often big dot
   - +/- - - - - - - - - - -
Chromophobe RCC [EGFR -3]

+
(84%2)

 +
+
 - +/- - + - - - - - - - -
Collecting duct carcinoma   +   - + +/- + - - - - - - - -
Neuroendocrine tumors   +   - - - - - - - - + + - -
Metanephric adenoma   +/-   - - + - - - - - - - - -
Wilms' tumor   +/-   - - + - - +/- +/- - +/- - + -
Liomyoma/leiomyosarcoma   +/-   - - + - - + + - - - - -
Rhabdomyosarcoma   +/-   - - + - - + - - +/- - - -
Hemangioma/angiosarcoma   +/-   - - + + + - - - - - - -
Hemangiopericytoma   -   - - + - - - - - - - - -
Angiomyolipoma   +/-   - - + - +/- +/- + + +/- - - -
Lipoma/liposarcoma   -   - - + - - - - - + - - -
Malignant fibrous histiocytoma   +/-   - - + - + + + - - - - -
Malignant lymphoma   -   - - + - +/- - - - - - - +

References:

  1. essentially copied from John N. Eble, M.D., Indiana University School of Medicine Indianapolis, IN and Stephan Storkel, M.D ., University of Witten/Herdecke, Wuppertal, Germany on the USCAP web site 4/24/01 (addition 5/12/03)
  2. Abrahams NA, et. al., "Chromophobe...", Histopathology 45(6):593-602, December 2004.
  3. Shah, Sejal, "Expression of EGFR...", Poster #29, ASCP annual meeting in Las Vegas, 10/2006 .