This is a chemical which can be detected in blood and mostly originating from peripheral blood and bone marrow monocyte white blood cells.

Situations In Which this Agent is Either not Detected or Probably not Elevated:

• cases in which the peripheral blood monocyte absolute count is elevated but without "bulky increase" of monocytes and monocytic precursors in the bone marrow

Situations in Which this Agent is Elevated:

• the myelodysplastic syndrome (MDS) of CMML (chronic myelomonocytic leukemia)