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| MPI
Predicting Early Distant Recurrence |
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Study distant recurrence data on 195 mastectomy
patients with ductal ca. NOS 1980-1983 (ages 29-87, mean 60, median
60; 13-57 months of follow up)
(all treated by modified radical mastectomy...those with central or medial primaries
or with positive nodes also getting radiation; prospective study & 7 different
persons calculated MPI; tumor size range 0.4-15 cm., median 2 cm.) |
The single best parameter at predicting:
| |
Distant recurrence status
of cases (n=195) |
|
number "yes" |
number "no" |
total cases |
| MPI < 0.60 |
10 (8%) |
112 (92%) |
122 |
| MPI > 0.60 |
27 (37%) |
46 (63%) |
73 |
| ALNN |
15 (13%) |
104 (87%) |
119 |
| ALNP |
22 (29%) |
54 (71%) |
76 |
| Tumor size < 2 cm. |
13 (13%) |
91 (87%) |
104 |
| Tumor size > 2cm. |
24 (26%) |
67 (74%) |
91 |
| MAI < 9 |
10 (9%) |
101 (81%) |
111 |
| MAI >9 |
27 (32%) |
57 (68%) |
84 |
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MPI plus node status refines further:
|
MPI
|
ALN
status
|
Distant recurrence status
of cases (n=195) |
| yes |
no |
total |
| < 0.60 |
ALNN |
8 |
91 (92%) |
99 |
| < 0.60 |
ALNP |
2 (9%) |
21 |
23 |
| > = 0.60 |
ALNN |
7 (54%) |
13 |
20 |
| > = 0.60 |
ALNP |
20 |
33 (63%) |
53 |
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| Reference: Baak, JPA, et.al., Prospective evaluation of
prognostic value of morphometry in patients with primary breast cancer |
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1999 - 2006, all rights reserved, Pathology Associates Of Lexington,
P.A. |
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