|
|
|
|
|
|
|
| Vasculitis |
| |
|
Timing of biopsies is critical because the DIF-identifiable deposits degrade so fast (lesion age 24 hours or less is optimal and after 48 hours of lesion age, a high chance of degraded, non-reactive deposits2).
|
H-S purpura |
cryoglob. vasculitis |
micro.
polyangiitis |
Wegener's |
Churg-Strauss |
| small vessel vasculitis signs & sx's |
yes |
yes |
yes |
yes |
yes |
| IgA dominant deposits |
yes (& +- others2) |
no |
no |
no |
no |
| cryoglob. in blood & vessels |
no |
yes |
no |
no |
no |
| ANCA in blood |
no |
no |
yes |
yes |
yes |
| necrotizing granulomas |
no |
no |
no |
yes |
yes |
| asthma & eosinophilia |
no |
no |
no |
no |
yes |
|
References:
- above chart mostly after Dr. Charles Jennette, Sem. in Diagnostic Path. Feb. 2001
page 11.
- Izuno GT, DIF chapter in Advances in Immunopathology, Clinics in Laboratory Medicine 6(1):97, March 1986 [EBS].
(most recent addition 25 June 2011) |
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1999 - 2006, all rights reserved, Pathology Associates Of Lexington,
P.A. |
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