• Emergency dermatopathology diagnosis notes & [flesh eating bacteria].
• Newborn (congenital) skin spots/moles/lesions.
• pigmentation disorders...streaks & spots & discolorations...HERE.
• Skin eruptions of pregnancy.
• Non-melanoma skin cancer: (A Maryland study in 2008 showed that, especially when cancers start at a younger age, those getting non-melanoma skin cancer have at least twice the rate of subsequently getting lung, colon, or breats cancer)
  • overview.
  • skin cancer types.
  • [(1) IHC DDX table.....(2) old IHC outline (some markers we don't have)]
  • dark moles & lesions mimicking malignant melanoma & the melanoma types & varieties.
  • lesions mimicking non-melanoma skin cancer (BCC & SCC).
  • benign lesions possibly confused with malignant adnexal counterparts.
  • layman source, Skin Cancer Foundation.
  • vascular lesions...careful!...HERE.

• About MELANOMA skin cancer: 
  • CARDINAL POINTS:
    1. pathology gross exam
    2. DX must be correct
    3. invasive vs. noninvasive: [HERE] regression is a stumbling block
    4. is it Clark level II vs III? [this & next 2, HERE]
    5. did you seek & rule out vascular invasion?
    6. did you seek & rule out perineural space invasion?
  • An overview, screening,  & melanoma variety definitions/criteria AND node nevi vs. met. melanoma.
  • AND, if you have lots of nevi, the new “MoleMapCD™” System of tracking your moles may be at a site near you (my son worked with the Columbia, S. C. inventor). And, there is another MoleMap where photos & dermatoscopic photos are taken of a "suspicious mole" and reviewed & diagnosed via internet by a specialized dermatologist known as a "dermatoscopist". In late 2011, MelApp came out for the iPhone for a photo of your suspicious mole and an app calculation of "riskiness".
  • basic melanoma histologic criteria, tables; template parameters & criteria.
  • pathology report parameters and their prognostic significance.
  • the Clark 6-parameter prognosis tables; use your pathology report to get a general idea of your odds of cure.
  • formula for your personal prognosis calculation (using your pathology report) with ability to adjust the survival intervals.
  • link to a good site with on-line info, article links, and staging & prognosis calculator. (NOTE: We continue to see on-line advice to use specialist pathologists for diagnoses. After 26 years in practice, our advice is, rather, to deal with pathologists [and all other physician service providers] who "care" and are qualified).
• skin cysts.
• Rough, scaly skin, Keratoderma, hyperkeratoses, genodermatoses, nail disorders.
• clavus & dozens of other localized friction & pressure-related callosities website file.
• hard to cure Palm & foot dermatitis.
• factitious (self inflicted) skin problems: dermatitis artefacta; think of this when you see odd abscesses, facial pigmentations & odd lesions, odd foreign body granulomata, and odd ulcers/excoriations (neurotic excoriations) or skin necroses, and certain types of hair loss (alopecia)...trichotillomania & traction alopecia.
• cutaneous sarcoidosis, what to do?
• skin scars:
• alopecia; an alopecia website.
• Dermatopathology on-line Czech outline and atlas.
• Medscape's Primary Care (photo) Dermatology Atlas of  skin disorders by lesion type, body location, and by search engine (access will require ID and password; another on-line atlas; New Zealand Dermatology website, DermNet, has search categories body area and symptom for patients and doctors.
• A dermatology website.
• A dermatopathology website.
• A podiatric dermatopathology lab site.
• A web site of information on blistering dermatoses.
• chronic cutaneous urticaria [CCU].

• DIF/DFA differential diagnosis notes:
  • differential diagnosis NOTES.
  • as a list of interesting cases solved by DIF/DFA.
  • preferred biopsy sites based on differential diagnosis.
  • as a decision tree or flow chart [pending].
• Anti-skin antibody testing by IFA...blood (serum) sample [here].
• Inflammatory dermatoses: [pending]
  • diseases in each histological pigeon-hole category, list [pending].
  •  as decision trees or flow charts [pending].
  • infectious, notes.

• Miscellaneous:
  • special hyperpigmentation:
    1. pellagra: a more acute case¹ has acanthosis & maybe some parakeratosis & can look like zinc-deficiency, late onset "acrodermatitis enteropathica" (which has superficial keratocytes with marked pallor & focal spongiosis) or necrolytic migratory erythema (flaccid bullae & parakeratosis & keratocyte pallor & vacuolation & a sort of superficial necrosis & separation). Chronic is hyperpigmented, symmetrical dermatosis that looks "cracked" like sunbaked mud (dermatitis, diarrhea, dementia)...niacin deficiency (J. SCMA Aug. 2003).
    2. acanthosis nigricans: Clinically hyperpigmented neck folds, armpits and intertriginous folds; histology reveals non-compact orthohyperkeratosis, papillomatosis, with minimal or no acanthosis or hyperpigmentation, the visually increased pigmentation due to the velvety papillomatosis "stacking" epidermisis virtically up the sides of the closely compacted papillated folds of skin; due to "benign"...associated with excessive niacin intake (e. g., to increase HDL cholesterol), & metabolic syndrome (see PCOS), & some others; "malignant"...when it heralds an internal malignancy, especially stomach cancer. Associated syndromes HERE.
    3. Addison's disease
    4. hemochromatosis, advanced

References:

1. McKee, Calonje, & Granter, Pathology of The Skin... Two volumes, 3rd Ed. 2005.

(posted 2001; latest addition 25 January 2012)